Watch “Your Inner Fish” from PBS online!

PBS just finished airing a three-part documentary based on paleontologist Neil Shubin’s book Your Inner Fish: A Journey into the 3.5-Billion-Year History of the Human Body, which he hosted. For anyone interested in evolution and how humans are related to the rest of the animal world, this is a must-see. It’s very well done, visually and with content. You can watch each of the episodes through the PBS website, Shubin tells me, for up to two weeks following the air date for each episode (thus, 4/24 for episode 1, May 1 for episode 2, and May 8 for episode 3. It’s April 25th today, and as of early this morning PST, episode 1 was still viewable. Just click on any of the three images below to view an episode!

Capture1 Capture2 Capture3

BOOK: Bone by Bone: Comparing Animal Skeletons

Sara Levine, Bone by Bone: Comparing Animal Skeletons (Minneapolis, MN: Lerner Publishing Group, 2013), 32 pp. Illustrated by T.S Spookytooth.

What animal would you be if your finger bones grew so long that they reached your feet? Or what if you had no leg bones but kept your arm bones? This picture book will keep you guessing as you read about how human skeletons are like—and unlike—those of other animals.

Although this book does not discuss evolutionary relationships (homology, common descent), it is a fun introduction to comparative anatomy for elementary students!

A visceral experience: “Body Worlds & the Brain” at OMSI, Portland, OR

Yesterday I headed to the Oregon Museum of Science and Industry in Portland, sans wife and child, to see the exhibit Body Worlds & the Brain (which opened on October 20th for a limited engagement). From Gunther von Hagens, the exhibit “includes more than 200 authentic human specimens and highlights neuroscience, brain development and performance. Through respectful, aesthetic displays, this all-new exhibition invites intensive study and profound reflection on the power, beauty, and fragility of the human body” (more info). The displays are shown along with large text panels discussing many aspects of being human, from anatomy and development to intelligence  and emotions.

I have always wanted to see one of these exhibits of plastinated cadavers, as I have heard from other people about what they liked about it or did not. Given that the bodies are obtained from individuals knowingly providing themselves for these artistic and didactic displays, there is not much I can complain about (much effort is made in getting this point across in the exhibit). Body Worlds is simply wondrous. My initial impression is amazement, but I am sure over the next few weeks I will think about certain aspects of the exhibit (I should see if the Portland libraries have this book: The Anatomy of Body Worlds: Critical Essays on the Plastinated Cadavers of Gunther von Hagens).

One text panel had the following words, which I think sums up such an endeavor: “The creative process generates the new by seeing the known in an unusual way. It is founded on a sense of wonder and fed by the ability to pursue an idea simply to satisfy our curiosity.” A truly visceral experience. I highly encourage folks in the Portland region to visit OMSI and peruse Body Worlds, especially the dynamic poses of many of the bodies and the various organs shown in stages of disease. How often does one get the opportunity to get so close and personal to what is – and could be – inside all of us?

Enjoy the photos, which I was given permission to take and post for media purposes.

Body Worlds & the Brain at OMSI (November 6, 2011)

Sagittal 3-D Slice Body (1999)

Close-up of Sagittal 3-D Slice Body (1999)

The Angel (2005)

The Digestive System

Blood vessel configuration of the arm

The Ponderer (2005)

The Ponderer (2005), showing the brain and spinal column

Elegance on Ice (2005)

The Ringman (2002)

A plastinated giraffe (2008), which made me think of what a project it must be to pack and ship these exhibits around the world

Interior of Giraffe (2008)

The Yoga Lady (2005)

Skull and brain of an infant

Lungs of a smoker

Sitting Ligament Body (2008)

Expanded skull

The human brain

Blood vessel configuration of a lamb

Obesity Revealed

OMSI visitors observing The Head-Diver (2006)

Another view of Giraffe (2008)

Guest Post – Defending the Sensible: Charles Darwin and the Anti-Vivisection Controversy

This guest post by Eric Michael Johnson is part of his Primate Diaries in Exile blog tour. Johnson is a PhD student in the history of evolutionary biology at UBC (he received his masters degree in primate behavior). You can follow other stops on his tour through his RSS feed, The Primate Diaries on Facebook, or by following him on Twitter.

His critics accused him of claiming that “Might is Right,” but did the founder of modern biology campaign to defend the least among us?

A physiological demonstration with vivisection of a dog.
Oil painting by Emile-Edouard Mouchy, 1832. (Wellcome Library, London.)

 

According to the British Medical Journal it resembled a crucifixion. The dogs were strapped to boards, backs down, and with their legs cinched outwards. In the stifling August heat their heavy panting was made only more intense by a suffocating fear. The accused was described as wearing a white apron “that was afterwards covered with blood” as he approached one of the struggling animals. His mouth was tied shut but when the blade entered the thin, pink flesh of his inner thigh the animal’s cries of agony were too much to bear.

Experienced medical men in attendance, including some of the nineteenth century’s top surgeons, were outraged and demanded that the animal’s torture cease. Thomas Joliffe Tufnell, President of the Royal College of Surgeons in Ireland, denounced the demonstration as a “cruel proceeding” and stormed to the operating table to cut the animal loose. Other physiologists objected to the interruption with one insisting, “That dog is insensible; he is not suffering anything.” But Tufnell held firm, “The dog is struggling hard to get free. I am a sportsman as well as a surgeon, and I will never see a dog bullied.” However, a vote was taken among the assembled members of the British Medical Association and the demonstration was allowed to continue.

A tube was then forced into the conscious animal’s femoral artery, the white hair of his belly stained red as the arterial pressure caused blood to spurt from the incision. Into the tube the accused injected pure alcohol. The result, continued the Journal, “was an immediate struggle, which almost immediately subsided. The animal became dead drunk.”

“Now, you see he’s insensible,” a physician snidely remarked to Tufnell.
“Yes,” Tufnell replied, “and he’ll never be sensible again, for he will die.”

Spattered with gore from the comatose animal, the accused, Dr. Eugene Magnan of Paris, insisted he would be quite well by that evening. The dog soon died. Magnan then turned to the second animal, opening the same artery as before but injecting absinthe into the wound. According to witnesses:

The animal struggled much, cried as far as it was able, showed other symptoms of great suffering, and ultimately–not long after the injection–had a fit of epilepsy.

This had been the point of Magnan’s August 13, 1874 demonstration: the physiological effects of alcohol and absinthe on the animal nervous system. It had been made possible by four physicians based in Norwich, England, all of whom now stood trial for actions taken that did “unlawfully illtreat, abuse, and torture certain animals.” Dr. Eugene Magnan, also listed as a defendant, was not present in the courtroom since he had fled the country back to France. Because it could not be proven that the four English physicians had been actively involved in the demonstration the charges were ultimately dismissed, though the court ruled that the case against them was proper and required them to pay all legal costs. However, in the court of public opinion they were guilty as charged.

Animal experimentation, or vivisection as it was known in the nineteenth century, had already been practiced for centuries (William Harvey’s famous dissections of deer in the 1620s had revealed the heart’s role in the circulatory system) but with the rise of scientific medicine more animal subjects were being “put to the blade” in the name of science. The physician George Hoggan described his own experience taking part in some of these dissections with dogs:

Hundreds of times I have seen when an animal writhed in pain, and thereby deranged the tissues, during a deliberate dissection; instead of being soothed, it would receive a slap and an angry order to be quiet and behave itself. . . Even when roughly grasped and thrown on the torture-trough, a low, complaining whine at such treatment would be all the protest made, and they would continue to lick the hand which bound them till their mouths were fixed in the gag.

Charles Darwin was well aware that these kinds of experiments took place, even using a similar example in his 1871 book The Descent of Man:

[E]veryone has heard of the dog suffering under vivisection who licked the hand of the operator; this man, unless he had a heart of stone, must have felt remorse to the last hour of his life.

As one of the most celebrated biologists in England Darwin was both a supporter of experimental physiology and was passionate about protecting animals from cruelty. As a local magistrate he regularly came across cases of cruelty to farm animals and, according to his biographer Janet Browne, “was inexorable in imposing fines and punishment.” In 1853 he waged a “private vendetta” against a Mr. Ainslie for cruelty to his carthorses, threatening to “have him up before a magistrate & his ploughman also.” According to his son, Francis Darwin, the man who many saw as advocating “might is right” was as disgusted by animal cruelty as he was by the human cruelty he experienced in slave holding societies:

The remembrance of screams, or other sounds heard in Brazil, when he was powerless to interfere with what he believed to be the torture of a slave, haunted him for years, especially at night. In smaller matters, where he could interfere, he did so vigorously. He returned one day from his walk pale and faint from having seen a horse ill-used, and from the agitation of violently remonstrating with the man. On another occasion he saw a horse-breaker teaching his son to ride, the little boy was frightened and the man was rough; my father stopped, and jumping out of the carriage reproved the man in no measured terms.

This sympathy extended to animals used in experimentation, as Darwin wrote to the Oxford zoologist Ray Lankester in 1871:

You ask about my opinion on vivisection. I quite agree that it is justifiable for real investigations on physiology; but not for mere damnable and detestable curiosity. It is a subject which makes me sick with horror, so I will not say another word about it, else I shall not sleep to-night.

However, Darwin did not take his own advice and, after the media uproar following Magnan’s demonstration and the ensuing court case, the notoriously reclusive naturalist spearheaded a campaign to regulate how vivisection was conducted in England.

Charles Darwin at his estate in Down, 1875. (H.P. Robinson/Bettmann/Corbis)

 

The year 1875 was a milestone for British animal rights activism. Building off the popular outrage over Magnan, the author, feminist, and animal rights campaigner Frances Power Cobbe formed the Society for the Protection of Animals Liable to Vivisection (and, later, the British Union for the Abolition of Vivisection, which continues to this day). With the assistance of sympathetic members of Parliament, Cobbe drafted a bill that would require regular inspections of physiological labs engaged in vivisection. Darwin heard of this activity through his daughter, Henrietta Litchfield, who was passionate about animal rights and had sent her father Cobbe’s petition to sign. Her letter had Darwin contemplating the issue “for some hours” and he delivered a considered and thoughtful response:

I conclude, if (as is likely) some experiments have been tried too often, or anesthetics have not been used when they could have been, the cure must be in the improvement of humanitarian feelings. Under this point of view I have rejoiced at the present agitation.

However, despite his conflicts over vivisection, Darwin’s opinion of the bill was that it would do little to protect animals and, at the same time, would result in a chilling effect on science:

[I]f such laws are passed, the result will assuredly be that physiology, which has been until within the last few years at a standstill in England, will languish or quite cease. . . I cannot at present see my way to sign any petition, without hearing what physiologists thought would be its effect, and then judging for myself.

Four months later Darwin, who rarely took any active role in politics, was in the midst of a political campaign to introduce his own bill to Parliament. As he wrote to his close friend Joseph Hooker, then-President of the Royal Society, “I worked all the time in London on the vivisection question . . . The object is to protect animals, and at the same time not to injure Physiology,” and he had already enlisted the support of “some half-dozen eminent scientific men.”

While the interest in protecting the scientific enterprise was an important aspect of what became known as the Playfair bill (after Dr. Lyon Playfair, the liberal member of Parliament who introduced the legislation) Darwin’s personal background advocating against animal cruelty and the fact that his son-in-law Robert Litchfield (Henrietta’s husband) was the one who helped Darwin write the bill suggests that animal rights was just as much a part of Darwin’s concern. In fact, the Playfair bill went beyond Cobbe’s in the protection of animals by including the British Association for the Advancement of Science (BAAS) guidelines that required anesthetic in all experiments, including for teaching purposes. As historian David Allen Feller wrote last year in his account of the 1875 antivivisection controversy:

Under the BAAS guidelines, not only was anesthesia required in experiments whenever possible, but an entire class of experiments, those conducted for mere demonstration purposes without any new scientific discovery in mind, were outlawed. This was not so under the [Cobbe] bill, which did not distinguish between classroom and purely scientific experiments. Inclusion of this provision of the BAAS guidelines was clearly intended by Darwin from the outset of his work on the bill. Darwin wrote to Burdon Sanderson and Huxley that he thought the BAAS guidelines would be the best compromise, and Darwin specifically noted the inclusion of a ban on the use of live animals for the purpose of demonstrative teaching.

Darwin is widely known for never taking part in any public discussions or debates on his theory of natural selection (leaving that to trusted friends such as Thomas Henry Huxley). His poor health and hatred of travel kept him at his estate in the countryside throughout most of his life. And yet, on the question of vivisection, Darwin not only traveled to London to help draft the Playfair bill, he returned when asked to testify by the Royal Commission when investigating the use of vivisection. During the questioning Darwin again insisted that experimentation on animals was important for the development of medical science. However, on the question of experiments carried out without anesthetic or ones inflicting pain unnecessarily, Darwin stated unequivocally that, “It deserves detestation and abhorrence.”

Those words became the basis upon which the Royal Commission recommended that vivisection be regulated. After quoting Darwin’s view in their report to the Queen, they went on to state:

This principle is accepted generally by the very highly educated men whose lives are devoted either to scientific investigation and education, or to the mitigation or the removal of the sufferings of their fellow creatures.

The following year The Cruelty to Animals Act of 1876 was passed by Parliament and signed into law.

Charles Darwin’s advocacy for animal rights has more than mere historical interest. Today it is commonplace for scientists, particularly those who work with animal models in their research, to oppose animal rights legislation as being fundamentally anti-science. However, as Darwin himself has demonstrated, it is possible (even necessary) for the pro-science position to be concerned with animal welfare. Being pro-science does not mean being pro-cruelty. There are currently some very good laws in place throughout England, Europe, and the United States that protect animals from unnecessary suffering in the pursuit of medical knowledge. However, the differences between countries continue to raise concerns about how much suffering should be permitted in animal research. This year saw the use of chimpanzees in medical experimentation banned throughout the European Union. At the same time, there are nearly 1,000 chimps used by federal researchers in the United States for vaccine, hepatitis C, and HIV research. Year after year legislation to ban the practice fails to gain support in Congress.

Ironically enough, many of the worst abusers of animals in the nineteenth century came from continental Europe, a region that is now the leader in animal rights legislation. If there is any justice in Eugene Magnan escaping prosecution for his actions 135 years ago, it may be that public outrage over his “demonstration” sparked a movement that, today, would provide him with no safe haven. There is little doubt that animal experimentation has resulted in some necessary medical breakthroughs. But, as in the nineteenth century controversy, Darwin’s own struggles with this research is something we would do well to remember.

References:

“Prosecution At Norwich. Experiments On Animals,” The British Medical Journal Vol. 2, No. 728 (Dec. 12, 1874), pp. 751-754.

Browne, J. (2002). Charles Darwin: The Power of Place. New Jersey: Princeton University Press.

Darwin, C. (1871). The Descent of Man, and Selection in Relation to Sex. New York: D. Appleton & Co.

Feller, D. (2009). Dog fight: Darwin as animal advocate in the antivivisection controversy of 1875 Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences, 40 (4), 265-271 DOI: 10.1016/j.shpsc.2009.09.004

ARTICLE: Darwin and Helmholtz on Imperfections of the Eye

ermann von Helmholtz (August 31, 1821 – September 8, 1894)

ermann von Helmholtz (August 31, 1821 – September 8, 1894)

From the journal Archives of Ophthalmology (Sept. 2010):

Darwin and Helmholtz on Imperfections of the Eye

Charles Darwin was curious about the workings of the eye and corresponded with William Bowman and Cornelis Donders about its structure and function. In his On the Origin of Species in 1859, he took care to make the case that even such a complex organ as the eye could arise by natural selection. In other contexts, Darwin also gave particular weight to observations that revealed imperfections in development of organic features. It was exactly this line of inquiry that was so telling against the creationist credo of supernatural design. Darwin made a point of this in the second edition of his The Descent of Man, and Selection in Relation to Sex (1874) in which he made special reference to the views of Hermann Helmholtz about the imperfections of the eye.

Cambridge Trip #8: Darwin’s Microscope at the Whipple Museum of the History of Science

Monday, 13 July 2009

Following a visit to the University Museum of Zoology in Cambridge, Richard and I headed over to the Whipple Museum of the History of Science to see the exhibit featuring Darwin’s microscope. On the way there, we checked out the Cambridge University Press Bookshop and spotted some interesting history of science spots:

Cambridge, England

Cambridge, England

Mobile Library, Cambridge, England

Mobile Library, Cambridge, England

At the bookshop, Richard went crazy and spent a deal on some Darwin books, including the not-so-cheap Charles Darwin’s Notebooks from the Voyage of the Beagle, edited by Gordon Chancellor and John van Wyhe. I bought one book, Charles Darwin: The Beagle Letters.

Darwin Display, Cambridge University Press Bookshop, Cambridge, England

Darwin Display, Cambridge University Press Bookshop, Cambridge, England

Darwin Display, Cambridge University Press Bookshop, Cambridge, England

Darwin Display, Cambridge University Press Bookshop, Cambridge, England

History of Science, Cambridge University Press Bookshop, Cambridge, England

History of Science, Cambridge University Press Bookshop, Cambridge, England

Ladybird Beetle, Cambridge, England

Ladybird Beetle, Cambridge, England

Cavendish Laboratory, Cambridge, England

Cavendish Laboratory, Cambridge, England

Cavendish Laboratory, Cambridge, England

Cavendish Laboratory, Cambridge, England

Plaque for J.J. Thompson, Cavendish Laboratory, Cambridge, England

Plaque for J.J. Thompson, Cavendish Laboratory, Cambridge, England

Crooked Doorway, Cambridge, England

Crooked Doorway, Cambridge, England

The Whipple Museum, which is in the same building that houses the Department of History and Philosophy of Science:

The Whipple Museum, University of Cambridge

The Whipple Museum, University of Cambridge

Department of History and Philosophy of Science, University of Cambridge

Department of History and Philosophy of Science, University of Cambridge

The exhibit Darwin’s Microscope (much more than a microscope was on display):

Darwins Microscope, Whipple Museum, University of Cambridge

Darwin's Microscope, Whipple Museum, University of Cambridge

Darwins Microscope, Whipple Museum, University of Cambridge

Darwin's Microscope, Whipple Museum, University of Cambridge

Darwins achromatic compound microscope, Whipple Museum, University of Cambridge

Darwin's achromatic compound microscope, Whipple Museum, University of Cambridge

Darwins achromatic compound microscope, Whipple Museum, University of Cambridge

Darwin's achromatic compound microscope (1847) for his barnacle research, Whipple Museum, University of Cambridge

Microscope slide storage, Whipple Museum, University of Cambridge

Microscope slide storage, Whipple Museum, University of Cambridge

Letter from Darwin to J.D. Hooker about the microscope, Whipple Museum of the History of Science, University of Cambridge

Letter from Darwin to J.D. Hooker about the microscope, Whipple Museum of the History of Science, University of Cambridge

Vol. II of Darwins A monograph on the sub-class Cirripedia (barnacles), Whipple Museum, University of Cambridge

Vol. II of Darwin's 'A monograph on the sub-class Cirripedia' (barnacles), Whipple Museum, University of Cambridge

In the same display case as the compound microscope were a bunch of evolutionary books and an older compound microscope similar to one Darwin had at Cambridge in the 1830s:

Older compound microscope, Whipple Museum, University of Cambridge

Older compound microscope, Whipple Museum, University of Cambridge

Evolutionary books, Whipple Museum, University of Cambridge

Evolutionary books, Whipple Museum, University of Cambridge

Evolutionary books, Whipple Museum, University of Cambridge

Evolutionary books, Whipple Museum, University of Cambridge

Part of this exhibit showcased The Darwin Correspondence Project, based at Cambridge (they have just published the 17th volume):

Darwin Correspondence Project display, Whipple Museum, University of Cambridge

Darwin Correspondence Project display, Whipple Museum, University of Cambridge

Darwin Correspondence Project display, Whipple Museum, University of Cambridge

Darwin Correspondence Project display, Whipple Museum, University of Cambridge

Darwin Correspondence Project display, Whipple Museum, University of Cambridge

Darwin Correspondence Project display, Whipple Museum, University of Cambridge

Darwin Correspondence Project display, Whipple Museum, University of Cambridge

Darwin Correspondence Project display, Whipple Museum, University of Cambridge

This image is not from the correspondence project, but from Richard, who, the day before leaving for Cambridge, ordered the new volume from his local bookshop, not realizing that he would be visiting the Cambridge University Press’s bookshop. Oh well.

Richards Darwin Correspondence Collection

Richard's Darwin Correspondence Collection

One display in the exhibit showcased in drawers a wide variety of Darwin memorabilia:

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

The caricature print in the image above I discussed in a post on my other blog, Transcribing Tyndall.

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

Darwin memorabilia, Whipple Museum, University of Cambridge

Another display showed late nineteenth-century responses to Darwin:

Responses to Darwin, Whipple Museum, University of Cambridge

Responses to Darwin, Whipple Museum, University of Cambridge

The caricature print above was also featured in the same post on Transcribing Tyndall.

Responses to Darwin, Whipple Museum, University of Cambridge

Responses to Darwin, Whipple Museum, University of Cambridge

Responses to Darwin, Whipple Museum, University of Cambridge

Responses to Darwin, Whipple Museum, University of Cambridge

Various posters and wall hangings:

Darwin wall hangings, Whipple Museum, University of Cambridge

Darwin wall hangings, Whipple Museum, University of Cambridge

Darwin wall hangings, Whipple Museum, University of Cambridge

Darwin wall hangings, Whipple Museum, University of Cambridge

Darwin wall hangings, Whipple Museum, University of Cambridge

Darwin wall hangings, Whipple Museum, University of Cambridge

Darwin wall hangings, Whipple Museum, University of Cambridge

Darwin wall hangings, Whipple Museum, University of Cambridge

Some shots from the rest of the museum:

Anatomical model of a fetus, Whipple Museum, University of Cambridge

Anatomical model of a fetus, Whipple Museum, University of Cambridge

Natural history displays, Whipple Museum, University of Cambridge

Natural history displays, Whipple Museum, University of Cambridge

Whipple Museum of the History of Science, University of Cambridge

Whipple Museum of the History of Science, University of Cambridge

Telescope, Whipple Museum, University of Cambridge

Telescope, Whipple Museum, University of Cambridge

Newton wants your money, Whipple Museum, University of Cambridge

Newton wants your money, Whipple Museum, University of Cambridge

R.S. Whipple, Founder of the Whipple Museum, University of Cambridge

R.S. Whipple, Founder of the Whipple Museum, University of Cambridge

After the Whipple Museum, we weren’t sure what to do next. Around the corner from the museum we ran into John van Wyhe, one of the Darwin historians I met at the conference (and owner of a Darwin groupie bike), as he was headed to his office at the building where the Whipple Museum is:

John van Wyhe, University of Cambridge

John van Wyhe, University of Cambridge. Photo by Richard Carter

Although it was Monday and Darwin’s room at Christ’s College was not open to the public, he quickly treated Richard and I to a look (other pictures from Christ’s I posted here). John was, after all, in charge of the restoration. Richard was also delighted to get his Beagle notebook signed by one of its editors. I will share photos from Darwin’s room in the next post.

You can view all the photos from my trip here, if you feel so inclined. Some of Richard’s Cambridge photos are here.

PREVIOUS: Cambridge Trip #7: Beetles, Finches and Barnacles at the University Museum of ZoologyCambridge Trip #6: Darwin the Geologist at the Sedgwick Museum of Earth SciencesCambridge Trip #5: Darwin Groupies Explore CambridgeCambridge Trip #4: Darwin in the Field Conference, Pt. 2Cambridge Trip #3: Darwin in the Field ConferenceCambridge Trip #2: Finding My WayCambridge Trip #1: Traveling